Endocrine Abstracts

Runx2 and Osterix(Osx) have been known as the master transcription factors for bone formation. However, genes that act downstream of both Runx2 and Osx have not been fully studied. To investigate downstream target genes of Runx2 and Osx, DNA microarray was conducted in calvaria of WT, Runx2ΔC/+, Osx+/−, and Runx2ΔC/+; Osx+/− double heterozygous mice designated WT, Runx2het, Osxhet, and Doub...